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Grape seed proanthocyanidins protect against streptozotocin-induced diabetic nephropathy by attenuating endoplasmic reticulum stress-induced apoptosis

Diabetic nephropathy (DN) is by far the most common cause of end-stage renal disease (ESRD) in industrial countries, accounting for ~45% of all new ESRD cases in the United States. Grape seed proanthocyanidin extracts (GSPE) are powerful antioxidants, with an antioxidant ability 50-fold greater than...

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Detalles Bibliográficos
Autores principales: Gao, Zhaoli, Liu, Guangyi, Hu, Zhao, Shi, Weiwei, Chen, Binbin, Zou, Peimei, Li, Xianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072170/
https://www.ncbi.nlm.nih.gov/pubmed/29901130
http://dx.doi.org/10.3892/mmr.2018.9140