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TIMP-3 suppresses the proliferation and migration of SMCs from the aortic neck of atherosclerotic AAA in rabbits, via decreased MMP-2 and MMP-9 activity, and reduced TNF-α expression

The present study investigated the role of tissue inhibitor of matrix metalloproteinase-3 (TIMP-3) in regulating the proliferation, migration, apoptosis and activity of matrix metalloproteinase (MMP)-2 and −9, during the development of an atherosclerotic abdominal artery aneurysm (AAA). Experiments...

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Detalles Bibliográficos
Autores principales: Zhai, Huan, Qi, Xun, Li, Zixuan, Zhang, Wei, Li, Chenguang, Ji, Lu, Xu, Ke, Zhong, Hongshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072177/
https://www.ncbi.nlm.nih.gov/pubmed/29956789
http://dx.doi.org/10.3892/mmr.2018.9224