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Synthesis and in vitro study of novel borneol derivatives as potent inhibitors of the influenza A virus

Herein, we present the design and synthesis of a series of novel heterocyclic derivatives of (–)-borneol and (–)-isoborneol as potent inhibitors of the influenza A virus. All compounds were tested for their toxicity against MDCK cells and for virus-inhibiting activity against the influenza virus A/P...

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Detalles Bibliográficos
Autores principales: Sokolova, A. S., Yarovaya, O. I., Semenova, M. D., Shtro, A. A., Orshanskaya, I. R., Zarubaev, V. V., Salakhutdinov, N. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072209/
https://www.ncbi.nlm.nih.gov/pubmed/30108810
http://dx.doi.org/10.1039/c6md00657d