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N-terminal truncated peroxisome proliferator-activated receptor-γ coactivator-1α alleviates phenylephrine-induced mitochondrial dysfunction and decreases lipid droplet accumulation in neonatal rat cardiomyocytes

N-terminal truncated peroxisome proliferator-activated receptor-γ coactivator-1α (NT-PGC-1α) is an alternative splice variant of PGC-1α. NT-PGC-1α exhibits stronger anti-obesity effects in adipose tissue than PGC-1α; however, NT-PGC-1α has not yet been investigated in neonatal rat cardiomyocytes (NR...

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Detalles Bibliográficos
Autores principales: Liu, Zuheng, Hua, Jinghai, Cai, Wanqiang, Zhan, Qiong, Lai, Wenyan, Zeng, Qingchun, Ren, Hao, Xu, Dingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072228/
https://www.ncbi.nlm.nih.gov/pubmed/29901150
http://dx.doi.org/10.3892/mmr.2018.9158