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Next-generation sequencing-based detection of EGFR, KRAS, BRAF, NRAS, PIK3CA, Her-2 and TP53 mutations in patients with non-small cell lung cancer

In recent years, the incidence of non-small cell lung cancer (NSCLC) has become the highest lethal rate of cancer worldwide. Molecular assays of EGFR, KRAS, BRAF, NRAS, PIK3CA and Her-2 are widely used to guide individualized treatment in NSCLC patients. Somatic mutations in 112 NSCLC patients, incl...

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Detalles Bibliográficos
Autores principales: Jing, Changwen, Mao, Xuhua, Wang, Zhuo, Sun, Kejing, Ma, Rong, Wu, Jianzhong, Cao, Haixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072231/
https://www.ncbi.nlm.nih.gov/pubmed/29956783
http://dx.doi.org/10.3892/mmr.2018.9210