Encapsulation of Chemotherapeutic Drug Melphalan in Cucurbit[7]uril: Effects on Its Alkylating Activity, Hydrolysis, and Cytotoxicity

[Image: see text] The formation of inclusion complexes between drugs and macrocycles has proven to be an effective strategy to increase solubilization and stabilization of the drug, while in several cases improving their biological activity. In this context, we explored the formation of an inclusion...

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Detalles Bibliográficos
Autores principales: Villarroel-Lecourt, Gustavo, Carrasco-Carvajal, Javiera, Andrade-Villalobos, Felipe, Solís-Egaña, Fresia, Merino-San Martín, Ignacio, Robinson-Duggon, José, Fuentealba, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072240/
https://www.ncbi.nlm.nih.gov/pubmed/30087942
http://dx.doi.org/10.1021/acsomega.8b01335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072240/
https://www.ncbi.nlm.nih.gov/pubmed/30087942
http://dx.doi.org/10.1021/acsomega.8b01335

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