Remarkably Efficient Blood–Brain Barrier Crossing Polyfluorene–Chitosan Nanoparticle Selectively Tweaks Amyloid Oligomer in Cerebrospinal Fluid and Aβ1–40

[Image: see text] Amyloid oligomers have emerged as a key neurotoxin in Alzheimer’s dementia. Amyloid aggregation inhibitors and modulators have therefore offered potential applications in therapeutics and diagnosis. However, crossing the blood–brain barrier (BBB) and finding the toxic aggregates am...

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Detalles Bibliográficos
Autores principales: Roy Chowdhury, Sayan, Mondal, Subrata, Muthuraj, Balakrishnan, Balaji, S. N., Trivedi, Vishal, Krishnan Iyer, Parameswar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072248/
https://www.ncbi.nlm.nih.gov/pubmed/30087934
http://dx.doi.org/10.1021/acsomega.8b00764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072248/
https://www.ncbi.nlm.nih.gov/pubmed/30087934
http://dx.doi.org/10.1021/acsomega.8b00764

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