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Remarkably Efficient Blood–Brain Barrier Crossing Polyfluorene–Chitosan Nanoparticle Selectively Tweaks Amyloid Oligomer in Cerebrospinal Fluid and Aβ1–40
[Image: see text] Amyloid oligomers have emerged as a key neurotoxin in Alzheimer’s dementia. Amyloid aggregation inhibitors and modulators have therefore offered potential applications in therapeutics and diagnosis. However, crossing the blood–brain barrier (BBB) and finding the toxic aggregates am...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072248/ https://www.ncbi.nlm.nih.gov/pubmed/30087934 http://dx.doi.org/10.1021/acsomega.8b00764 |