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HSV-TK/GCV can induce cytotoxicity of retinoblastoma cells through autophagy inhibition by activating MAPK/ERK

Retinoblastoma is an severe ophthalmic disease and the most common type intraocular malignant tumor, particularly in infants. Currently, few drugs and therapies are available. Gene therapy has been considered to be a potential treatment to cure cancer effectively and Herpes simplex virus type 1 thym...

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Detalles Bibliográficos
Autores principales: Yi, Quan-Yong, Bai, Zhi-Sha, Cai, Bin, Chen, Nan, Chen, Li-Shuang, Yuan, Tao, Mao, Jing-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072295/
https://www.ncbi.nlm.nih.gov/pubmed/29845211
http://dx.doi.org/10.3892/or.2018.6454