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HSV-TK/GCV can induce cytotoxicity of retinoblastoma cells through autophagy inhibition by activating MAPK/ERK
Retinoblastoma is an severe ophthalmic disease and the most common type intraocular malignant tumor, particularly in infants. Currently, few drugs and therapies are available. Gene therapy has been considered to be a potential treatment to cure cancer effectively and Herpes simplex virus type 1 thym...
Autores principales: | Yi, Quan-Yong, Bai, Zhi-Sha, Cai, Bin, Chen, Nan, Chen, Li-Shuang, Yuan, Tao, Mao, Jing-Hai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072295/ https://www.ncbi.nlm.nih.gov/pubmed/29845211 http://dx.doi.org/10.3892/or.2018.6454 |
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