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Ophiopogonin B suppresses the metastasis and angiogenesis of A549 cells in vitro and in vivo by inhibiting the EphA2/Akt signaling pathway

Lung adenocarcinoma is the most common metastatic cancer, and is associated with high patient mortality. Therefore, investigation of anti-metastatic treatments for lung adenocarcinoma is crucial. Ophiopogonin B (OP-B) is a bioactive component of Radix Ophiopogon Japonicus, which is often used in Chi...

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Detalles Bibliográficos
Autores principales: Chen, Meijuan, Hu, Cheng, Guo, Yuanyuan, Jiang, Rilei, Jiang, Huimin, Zhou, Yu, Fu, Haian, Wu, Mianhua, Zhang, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072400/
https://www.ncbi.nlm.nih.gov/pubmed/29956803
http://dx.doi.org/10.3892/or.2018.6531