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Distinct and evolutionary conserved structural features of the human nuclear exosome complex

The nuclear RNA exosome complex mediates the processing of structured RNAs and the decay of aberrant non-coding RNAs, an important function particularly in human cells. Most mechanistic studies to date have focused on the yeast system. Here, we reconstituted and studied the properties of a recombina...

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Detalles Bibliográficos
Autores principales: Gerlach, Piotr, Schuller, Jan M, Bonneau, Fabien, Basquin, Jérôme, Reichelt, Peter, Falk, Sebastian, Conti, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072439/
https://www.ncbi.nlm.nih.gov/pubmed/30047866
http://dx.doi.org/10.7554/eLife.38686