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Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades

To identify biomarkers for glioma growth, invasion and progression, we used a candidate gene approach in mouse models with two complementary brain tumour phenotypes, developing either slow-growing, diffusely infiltrating gliomas or highly proliferative, non-invasive primitive neural tumours. In a mi...

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Detalles Bibliográficos
Autores principales: Li, Ningning, Zhang, Ying, Sidlauskas, Kastytis, Ellis, Matthew, Evans, Ian, Frankel, Paul, Lau, Joanne, El-Hassan, Tedani, Guglielmi, Loredana, Broni, Jessica, Richard-Loendt, Angela, Brandner, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072706/
https://www.ncbi.nlm.nih.gov/pubmed/29720725
http://dx.doi.org/10.1038/s41388-018-0277-1