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Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM

Uptake of vitamin B12 is essential for many prokaryotes, but in most cases the membrane proteins involved are yet to be identified. We present the biochemical characterization and high-resolution crystal structure of BtuM, a predicted bacterial vitamin B12 uptake system. BtuM binds vitamin B12 in it...

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Detalles Bibliográficos
Autores principales: Rempel, S., Colucci, E., de Gier, J. W., Guskov, A., Slotboom, D. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072759/
https://www.ncbi.nlm.nih.gov/pubmed/30072686
http://dx.doi.org/10.1038/s41467-018-05441-9