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Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
Uptake of vitamin B12 is essential for many prokaryotes, but in most cases the membrane proteins involved are yet to be identified. We present the biochemical characterization and high-resolution crystal structure of BtuM, a predicted bacterial vitamin B12 uptake system. BtuM binds vitamin B12 in it...
Autores principales: | Rempel, S., Colucci, E., de Gier, J. W., Guskov, A., Slotboom, D. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072759/ https://www.ncbi.nlm.nih.gov/pubmed/30072686 http://dx.doi.org/10.1038/s41467-018-05441-9 |
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