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oxLDL inhibits differentiation and functional activity of osteoclasts via scavenger receptor-A mediated autophagy and cathepsin K secretion

Resorptive activity of osteoclasts is important for maintaining bone homeostasis. Endogenous compounds such as oxidized low density lipoprotein (oxLDL) have been shown to disturb this activity. While some studies have investigated the effects of oxLDL on the process of osteoclastogenesis, the underl...

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Detalles Bibliográficos
Autores principales: Dawodu, Damilola, Patecki, Margret, Hegermann, Jan, Dumler, Inna, Haller, Hermann, Kiyan, Yulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072764/
https://www.ncbi.nlm.nih.gov/pubmed/30072716
http://dx.doi.org/10.1038/s41598-018-29963-w