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Loss of glutamate signaling from the thalamus to dorsal striatum impairs motor function and slows the execution of learned behaviors

Parkinson’s disease (PD) is primarily associated with the degeneration of midbrain dopamine neurons, but it is now appreciated that pathological processes like Lewy-body inclusions and cell loss affect several other brain regions, including the central lateral (CL) and centromedian/parafascicular (C...

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Detalles Bibliográficos
Autores principales: Melief, Erica J., McKinley, Jonathan W., Lam, Jonathan Y., Whiteley, Nicole M., Gibson, Alec W., Neumaier, John F., Henschen, Charles W., Palmiter, Richard D., Bamford, Nigel S., Darvas, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072777/
https://www.ncbi.nlm.nih.gov/pubmed/30083593
http://dx.doi.org/10.1038/s41531-018-0060-6