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Loss of glutamate signaling from the thalamus to dorsal striatum impairs motor function and slows the execution of learned behaviors
Parkinson’s disease (PD) is primarily associated with the degeneration of midbrain dopamine neurons, but it is now appreciated that pathological processes like Lewy-body inclusions and cell loss affect several other brain regions, including the central lateral (CL) and centromedian/parafascicular (C...
Autores principales: | Melief, Erica J., McKinley, Jonathan W., Lam, Jonathan Y., Whiteley, Nicole M., Gibson, Alec W., Neumaier, John F., Henschen, Charles W., Palmiter, Richard D., Bamford, Nigel S., Darvas, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072777/ https://www.ncbi.nlm.nih.gov/pubmed/30083593 http://dx.doi.org/10.1038/s41531-018-0060-6 |
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