TOFA induces cell cycle arrest and apoptosis in ACHN and 786-O cells through inhibiting PI3K/Akt/mTOR pathway

Cancer cells usually have a high requirement for fatty acids in order to meet the rapid proliferation and metabolism. Acetyl-CoA carboxylase-α(ACCA) catalyzes the carboxylation of acetyl-CoA to malonyl-CoA and has been a rate-limiting enzyme in the synthesis of long chain fatty acid and cellular ene...

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Detalles Bibliográficos
Autores principales: He, Dejiao, Sun, Xuan, Yang, Hongxia, Li, Xiaoli, Yang, Dingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072807/
https://www.ncbi.nlm.nih.gov/pubmed/30087714
http://dx.doi.org/10.7150/jca.26374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072807/
https://www.ncbi.nlm.nih.gov/pubmed/30087714
http://dx.doi.org/10.7150/jca.26374

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