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Knockdown of C1GalT1 inhibits radioresistance of human esophageal cancer cells through modifying β1-integrin glycosylation

Radiotherapy has played a limited role for the treatment of human esophageal cancer owing to the risk of tumor radioresistance. Core 1 β1, 3-galactosyltransferase (C1GalT1), which catalyzes the formation of core 1 O-glycan structures, is frequently overexpressed during tumorigenesis. However, the ex...

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Detalles Bibliográficos
Autores principales: Zhang, Chuanyi, Deng, Xinzhou, Qiu, Li, Peng, Feng, Geng, Shanshan, Shen, Li, Luo, Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072818/
https://www.ncbi.nlm.nih.gov/pubmed/30087707
http://dx.doi.org/10.7150/jca.25252