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Innate Immunity Induced by the Major Allergen Alt a 1 From the Fungus Alternaria Is Dependent Upon Toll-Like Receptors 2/4 in Human Lung Epithelial Cells

Allergens are molecules that elicit a hypersensitive inflammatory response in sensitized individuals and are derived from a variety of sources. Alt a 1 is the most clinically important secreted allergen of the ubiquitous fungus, Alternaria. It has been shown to be a major allergen causing IgE-mediat...

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Detalles Bibliográficos
Autores principales: Hayes, Tristan, Rumore, Amanda, Howard, Brad, He, Xin, Luo, Mengyao, Wuenschmann, Sabina, Chapman, Martin, Kale, Shiv, Li, Liwu, Kita, Hirohito, Lawrence, Christopher B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072870/
https://www.ncbi.nlm.nih.gov/pubmed/30100902
http://dx.doi.org/10.3389/fimmu.2018.01507