Genetic ablation of tau improves mitochondrial function and cognitive abilities in the hippocampus

Tau is a key protein for microtubule stability; however, post-translationally modified tau contributes to neurodegenerative diseases by forming tau aggregates in the neurons. Previous reports from our group and others have shown that pathological forms of tau are toxic and impair mitochondrial funct...

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Detalles Bibliográficos
Autores principales: Jara, Claudia, Aránguiz, Alejandra, Cerpa, Waldo, Tapia-Rojas, Cheril, Quintanilla, Rodrigo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072970/
https://www.ncbi.nlm.nih.gov/pubmed/30077079
http://dx.doi.org/10.1016/j.redox.2018.07.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072970/
https://www.ncbi.nlm.nih.gov/pubmed/30077079
http://dx.doi.org/10.1016/j.redox.2018.07.010

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