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Boldine Improves Kidney Damage in the Goldblatt 2K1C Model Avoiding the Increase in TGF-β
Boldine, a major aporphine alkaloid found in the Chilean boldo tree, is a potent antioxidant. Oxidative stress plays a detrimental role in the pathogenesis of kidney damage in renovascular hypertension (RVH). The activation of the renin-angiotensin system (RAS) is crucial to the development and prog...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073111/ https://www.ncbi.nlm.nih.gov/pubmed/29941815 http://dx.doi.org/10.3390/ijms19071864 |