Label-Free Quantitative Proteomics Combined with Biological Validation Reveals Activation of Wnt/β-Catenin Pathway Contributing to Trastuzumab Resistance in Gastric Cancer

Resistance to trastuzumab, which specifically target HER2-positive breast and gastric cancer, can develop ultimately in cancer patients. However, the underlying mechanisms of resistance in gastric cancer have not been fully elucidated. Here, we established trastuzumab-resistant MKN45 and NCI N87 gas...

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Detalles Bibliográficos
Autores principales: Liu, Wenhu, Yuan, Jiangbei, Liu, Zhenzhong, Zhang, Jianwu, Chang, Jinxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073113/
https://www.ncbi.nlm.nih.gov/pubmed/29986466
http://dx.doi.org/10.3390/ijms19071981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073113/
https://www.ncbi.nlm.nih.gov/pubmed/29986466
http://dx.doi.org/10.3390/ijms19071981

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