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Regulation of CYP2J2 and EET Levels in Cardiac Disease and Diabetes

Cytochrome P450 2J2 (CYP2J2) is a known arachidonic acid (AA) epoxygenase that mediates the formation of four bioactive regioisomers of cis-epoxyeicosatrienoic acids (EETs). Although its expression in the liver is low, CYP2J2 is mainly observed in extrahepatic tissues, including the small intestine,...

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Detalles Bibliográficos
Autores principales: Aliwarga, Theresa, Evangelista, Eric A., Sotoodehnia, Nona, Lemaitre, Rozenn N., Totah, Rheem A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073148/
https://www.ncbi.nlm.nih.gov/pubmed/29966295
http://dx.doi.org/10.3390/ijms19071916