Succinate Accumulation Is Associated with a Shift of Mitochondrial Respiratory Control and HIF-1α Upregulation in PTEN Negative Prostate Cancer Cells

The idea of using metabolic aberrations as targets for diagnosis or therapeutic intervention has recently gained increasing interest. In a previous study, our group discovered intriguing differences in the oxidative mitochondrial respiration capacity of benign and prostate cancer (PCa) cells. In par...

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Detalles Bibliográficos
Autores principales: Weber, Anja, Klocker, Helmut, Oberacher, Herbert, Gnaiger, Erich, Neuwirt, Hannes, Sampson, Natalie, Eder, Iris E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073160/
https://www.ncbi.nlm.nih.gov/pubmed/30037119
http://dx.doi.org/10.3390/ijms19072129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073160/
https://www.ncbi.nlm.nih.gov/pubmed/30037119
http://dx.doi.org/10.3390/ijms19072129

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