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Negative feedback via RSK modulates Erk‐dependent progression from naïve pluripotency

Mitogen‐activated protein kinase (MAPK)/extracellular signal‐regulated kinase (ERK) signalling is implicated in initiation of embryonic stem (ES) cell differentiation. The pathway is subject to complex feedback regulation. Here, we examined the ERK‐responsive phosphoproteome in ES cells and identifi...

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Detalles Bibliográficos
Autores principales: Nett, Isabelle RE, Mulas, Carla, Gatto, Laurent, Lilley, Kathryn S, Smith, Austin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073214/
https://www.ncbi.nlm.nih.gov/pubmed/29895711
http://dx.doi.org/10.15252/embr.201745642