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Negative feedback via RSK modulates Erk‐dependent progression from naïve pluripotency
Mitogen‐activated protein kinase (MAPK)/extracellular signal‐regulated kinase (ERK) signalling is implicated in initiation of embryonic stem (ES) cell differentiation. The pathway is subject to complex feedback regulation. Here, we examined the ERK‐responsive phosphoproteome in ES cells and identifi...
Autores principales: | Nett, Isabelle RE, Mulas, Carla, Gatto, Laurent, Lilley, Kathryn S, Smith, Austin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073214/ https://www.ncbi.nlm.nih.gov/pubmed/29895711 http://dx.doi.org/10.15252/embr.201745642 |
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