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Farnesoid X Receptor Activation Enhances Transforming Growth Factor β-Induced Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma Cells

Farnesoid X receptor (FXR) is a receptor for bile acids and plays an important role in the regulation of bile acid metabolism in the liver. Although FXR has been shown to affect hepatocarcinogenesis through both direct and indirect mechanisms, potential roles of FXR in epithelial–mesenchymal transit...

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Detalles Bibliográficos
Autores principales: Kainuma, Masahiko, Takada, Ichiro, Makishima, Makoto, Sano, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073264/
https://www.ncbi.nlm.nih.gov/pubmed/29958417
http://dx.doi.org/10.3390/ijms19071898