Multiple Layers of CDK5R1 Regulation in Alzheimer’s Disease Implicate Long Non-Coding RNAs

Cyclin-dependent kinase 5 regulatory subunit 1 (CDK5R1) gene encodes for p35, the main activator of Cyclin-dependent kinase 5 (CDK5). The active p35/CDK5 complex is involved in numerous aspects of brain development and function, and its deregulation is closely associated to Alzheimer’s disease (AD)...

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Detalles Bibliográficos
Autores principales: Spreafico, Marco, Grillo, Barbara, Rusconi, Francesco, Battaglioli, Elena, Venturin, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073344/
https://www.ncbi.nlm.nih.gov/pubmed/29997370
http://dx.doi.org/10.3390/ijms19072022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073344/
https://www.ncbi.nlm.nih.gov/pubmed/29997370
http://dx.doi.org/10.3390/ijms19072022

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