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The Role of the Arginine in the Conserved N-Terminal Domain RLFDQxFG Motif of Human Small Heat Shock Proteins HspB1, HspB4, HspB5, HspB6, and HspB8

Although the N-terminal domain of vertebrate small heat shock proteins (sHsp) is poorly conserved, it contains a core motif preserved in many members of the sHsp family. The role of this RLFDQxFG motif remains elusive. We analyzed the specific role of the first arginine residue of this conserved oct...

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Detalles Bibliográficos
Autores principales: Shatov, Vladislav M., Weeks, Stephen D., Strelkov, Sergei V., Gusev, Nikolai B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073470/
https://www.ncbi.nlm.nih.gov/pubmed/30036999
http://dx.doi.org/10.3390/ijms19072112