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Cecropin A Modulates Tight Junction-Related Protein Expression and Enhances the Barrier Function of Porcine Intestinal Epithelial Cells by Suppressing the MEK/ERK Pathway

Inflammatory bowel disease (IBD) in humans and animals is associated with bacterial infection and intestinal barrier dysfunction. Cecropin A, an antimicrobial peptide, has antibacterial activity against pathogenic bacteria. However, the effect of cecropin A on intestinal barrier function and its rel...

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Detalles Bibliográficos
Autores principales: Zhai, Zhenya, Ni, Xiaojun, Jin, Chenglong, Ren, Wenkai, Li, Jie, Deng, Jinping, Deng, Baichuan, Yin, Yulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073479/
https://www.ncbi.nlm.nih.gov/pubmed/30004434
http://dx.doi.org/10.3390/ijms19071941