miR-196a Is Able to Restore the Aggressive Phenotype of Annexin A1 Knock-Out in Pancreatic Cancer Cells by CRISPR/Cas9 Genome Editing

Annexin A1 (ANXA1) is a Ca(2+)-binding protein that is involved in pancreatic cancer (PC) progression. It is able to mediate cytoskeletal organization maintaining a malignant phenotype. Our previous studies showed that ANXA1 Knock-Out (KO) MIA PaCa-2 cells partially lost their migratory and invasive...

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Detalles Bibliográficos
Autores principales: Belvedere, Raffaella, Saggese, Pasquale, Pessolano, Emanuela, Memoli, Domenico, Bizzarro, Valentina, Rizzo, Francesca, Parente, Luca, Weisz, Alessandro, Petrella, Antonello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073506/
https://www.ncbi.nlm.nih.gov/pubmed/29986379
http://dx.doi.org/10.3390/ijms19071967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073506/
https://www.ncbi.nlm.nih.gov/pubmed/29986379
http://dx.doi.org/10.3390/ijms19071967

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