Recent Trends and Applications of Molecular Modeling in GPCR–Ligand Recognition and Structure-Based Drug Design

G protein-coupled receptors represent the largest family of human membrane proteins and are modulated by a variety of drugs and endogenous ligands. Molecular modeling techniques, especially enhanced sampling methods, have provided significant insight into the mechanism of GPCR–ligand recognition. No...

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Detalles Bibliográficos
Autores principales: Yuan, Xiaojing, Xu, Yechun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073596/
https://www.ncbi.nlm.nih.gov/pubmed/30036949
http://dx.doi.org/10.3390/ijms19072105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073596/
https://www.ncbi.nlm.nih.gov/pubmed/30036949
http://dx.doi.org/10.3390/ijms19072105

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