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Detection of the Mitochondrial Membrane Potential by the Cationic Dye JC-1 in L1210 Cells with Massive Overexpression of the Plasma Membrane ABCB1 Drug Transporter

JC-1, a cationic fluorescent dye when added to living cells, is known to be localized exclusively in mitochondria, particularly in good physiological conditions characterized by sufficient mitochondrial membrane potential (ΔΨ). The accumulation of JC-1 in these organelles leads to the formation J-ag...

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Detalles Bibliográficos
Autores principales: Elefantova, Katarina, Lakatos, Boris, Kubickova, Jana, Sulova, Zdena, Breier, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073605/
https://www.ncbi.nlm.nih.gov/pubmed/29986516
http://dx.doi.org/10.3390/ijms19071985