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Circulating Tumour DNA Analysis for Tumour Genome Characterisation and Monitoring Disease Burden in Extramedullary Multiple Myeloma

Mutational characterisation in extramedullary multiple myeloma (EM-MM) patients is challenging due to inaccessible EM plasmacytomas, unsafe nature of multiple biopsies and the spatial and temporal genomic heterogeneity apparent in MM (Graphical abstract). Conventional monitoring of disease burden is...

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Detalles Bibliográficos
Autores principales: Mithraprabhu, Sridurga, Sirdesai, Shreerang, Chen, Maoshan, Khong, Tiffany, Spencer, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073672/
https://www.ncbi.nlm.nih.gov/pubmed/29937522
http://dx.doi.org/10.3390/ijms19071858