Activating the Anaphase Promoting Complex to Enhance Genomic Stability and Prolong Lifespan

In aging cells, genomic instability is now recognized as a hallmark event. Throughout life, cells encounter multiple endogenous and exogenous DNA damaging events that are mostly repaired, but inevitably DNA mutations, chromosome rearrangements, and epigenetic deregulation begins to mount. Now that p...

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Detalles Bibliográficos
Autor principal: Harkness, Troy A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073722/
https://www.ncbi.nlm.nih.gov/pubmed/29954095
http://dx.doi.org/10.3390/ijms19071888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073722/
https://www.ncbi.nlm.nih.gov/pubmed/29954095
http://dx.doi.org/10.3390/ijms19071888

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