Mechanisms of Tumor Growth Inhibition by Depletion of γ-Glutamylcyclotransferase (GGCT): A Novel Molecular Target for Anticancer Therapy

γ-Glutamylcyclotransferase (GGCT), which is one of the major enzymes involved in glutathione metabolism, is upregulated in a wide range of cancers—glioma, breast, lung, esophageal, gastric, colorectal, urinary bladder, prostate, cervical, ovarian cancers and osteosarcoma—and promotes cancer progress...

Descripción completa

Detalles Bibliográficos
Autores principales: Kageyama, Susumu, Ii, Hiromi, Taniguchi, Keiko, Kubota, Shigehisa, Yoshida, Tetsuya, Isono, Takahiro, Chano, Tokuhiro, Yoshiya, Taku, Ito, Kosei, Yoshiki, Tatsuhiro, Kawauchi, Akihiro, Nakata, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073726/
https://www.ncbi.nlm.nih.gov/pubmed/30011933
http://dx.doi.org/10.3390/ijms19072054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073726/
https://www.ncbi.nlm.nih.gov/pubmed/30011933
http://dx.doi.org/10.3390/ijms19072054

Ejemplares similares