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Mechanisms of Tumor Growth Inhibition by Depletion of γ-Glutamylcyclotransferase (GGCT): A Novel Molecular Target for Anticancer Therapy
γ-Glutamylcyclotransferase (GGCT), which is one of the major enzymes involved in glutathione metabolism, is upregulated in a wide range of cancers—glioma, breast, lung, esophageal, gastric, colorectal, urinary bladder, prostate, cervical, ovarian cancers and osteosarcoma—and promotes cancer progress...
Autores principales: | Kageyama, Susumu, Ii, Hiromi, Taniguchi, Keiko, Kubota, Shigehisa, Yoshida, Tetsuya, Isono, Takahiro, Chano, Tokuhiro, Yoshiya, Taku, Ito, Kosei, Yoshiki, Tatsuhiro, Kawauchi, Akihiro, Nakata, Susumu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073726/ https://www.ncbi.nlm.nih.gov/pubmed/30011933 http://dx.doi.org/10.3390/ijms19072054 |
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