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Resveratrol Modulates SIRT1 and DNMT Functions and Restores LINE-1 Methylation Levels in ARPE-19 Cells under Oxidative Stress and Inflammation

The role of epigenetic alterations in the pathogenesis of retinal degenerative diseases, including age-related macular degeneration (AMD), has been pending so far. Our study investigated the effect of oxidative stress and inflammation on DNA methyltransferases (DNMTs) and Sirtuin 1 (SIRT1) functions...

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Detalles Bibliográficos
Autores principales:	Maugeri, Andrea, Barchitta, Martina, Mazzone, Maria Grazia, Giuliano, Francesco, Basile, Guido, Agodi, Antonella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073744/ https://www.ncbi.nlm.nih.gov/pubmed/30037017 http://dx.doi.org/10.3390/ijms19072118

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