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Involvement of Allosteric Effect and K(Ca) Channels in Crosstalk between β(2)-Adrenergic and Muscarinic M(2) Receptors in Airway Smooth Muscle

To advance the development of bronchodilators for asthma and chronic obstructive pulmonary disease (COPD), this study was designed to investigate the mechanism of functional antagonism between β(2)-adrenergic and muscarinic M(2) receptors, focusing on allosteric effects and G proteins/ion channels c...

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Detalles Bibliográficos
Autores principales: Kume, Hiroaki, Nishiyama, Osamu, Isoya, Takaaki, Higashimoto, Yuji, Tohda, Yuji, Noda, Yukihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073859/
https://www.ncbi.nlm.nih.gov/pubmed/29987243
http://dx.doi.org/10.3390/ijms19071999