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Involvement of Allosteric Effect and K(Ca) Channels in Crosstalk between β(2)-Adrenergic and Muscarinic M(2) Receptors in Airway Smooth Muscle
To advance the development of bronchodilators for asthma and chronic obstructive pulmonary disease (COPD), this study was designed to investigate the mechanism of functional antagonism between β(2)-adrenergic and muscarinic M(2) receptors, focusing on allosteric effects and G proteins/ion channels c...
Autores principales: | Kume, Hiroaki, Nishiyama, Osamu, Isoya, Takaaki, Higashimoto, Yuji, Tohda, Yuji, Noda, Yukihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073859/ https://www.ncbi.nlm.nih.gov/pubmed/29987243 http://dx.doi.org/10.3390/ijms19071999 |
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