Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in liver tumours (TARDOX): a single-centre, open-label, phase 1 trial

BACKGROUND: Previous preclinical research has shown that extracorporeal devices can be used to enhance the delivery and distribution of systemically administered anticancer drugs, resulting in increased intratumoural concentrations. We aimed to assess the safety and feasibility of targeted release a...

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Detalles Bibliográficos
Autores principales: Lyon, Paul C, Gray, Michael D, Mannaris, Christophoros, Folkes, Lisa K, Stratford, Michael, Campo, Leticia, Chung, Daniel Y F, Scott, Shaun, Anderson, Mark, Goldin, Robert, Carlisle, Robert, Wu, Feng, Middleton, Mark R, Gleeson, Fergus V, Coussios, Constantin C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lancet Pub. Group 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073884/
https://www.ncbi.nlm.nih.gov/pubmed/30001990
http://dx.doi.org/10.1016/S1470-2045(18)30332-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073884/
https://www.ncbi.nlm.nih.gov/pubmed/30001990
http://dx.doi.org/10.1016/S1470-2045(18)30332-2

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