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Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in liver tumours (TARDOX): a single-centre, open-label, phase 1 trial
BACKGROUND: Previous preclinical research has shown that extracorporeal devices can be used to enhance the delivery and distribution of systemically administered anticancer drugs, resulting in increased intratumoural concentrations. We aimed to assess the safety and feasibility of targeted release a...
Autores principales: | Lyon, Paul C, Gray, Michael D, Mannaris, Christophoros, Folkes, Lisa K, Stratford, Michael, Campo, Leticia, Chung, Daniel Y F, Scott, Shaun, Anderson, Mark, Goldin, Robert, Carlisle, Robert, Wu, Feng, Middleton, Mark R, Gleeson, Fergus V, Coussios, Constantin C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lancet Pub. Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073884/ https://www.ncbi.nlm.nih.gov/pubmed/30001990 http://dx.doi.org/10.1016/S1470-2045(18)30332-2 |
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