CFTR Deletion Confers Mitochondrial Dysfunction and Disrupts Lipid Homeostasis in Intestinal Epithelial Cells

Background: Cystic Fibrosis (CF) is a genetic disease in which the intestine exhibits oxidative and inflammatory markers. As mitochondria are the central source and the main target of reactive oxygen species, we hypothesized that cystic fibrosis transmembrane conductance regulator (CFTR) defect lead...

Descripción completa

Detalles Bibliográficos
Autores principales: Kleme, Marie L., Sané, Alain, Garofalo, Carole, Seidman, Ernest, Brochiero, Emmanuelle, Berthiaume, Yves, Levy, Emile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073936/
https://www.ncbi.nlm.nih.gov/pubmed/29954133
http://dx.doi.org/10.3390/nu10070836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073936/
https://www.ncbi.nlm.nih.gov/pubmed/29954133
http://dx.doi.org/10.3390/nu10070836

Ejemplares similares