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CFTR Deletion Confers Mitochondrial Dysfunction and Disrupts Lipid Homeostasis in Intestinal Epithelial Cells
Background: Cystic Fibrosis (CF) is a genetic disease in which the intestine exhibits oxidative and inflammatory markers. As mitochondria are the central source and the main target of reactive oxygen species, we hypothesized that cystic fibrosis transmembrane conductance regulator (CFTR) defect lead...
Autores principales: | Kleme, Marie L., Sané, Alain, Garofalo, Carole, Seidman, Ernest, Brochiero, Emmanuelle, Berthiaume, Yves, Levy, Emile |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073936/ https://www.ncbi.nlm.nih.gov/pubmed/29954133 http://dx.doi.org/10.3390/nu10070836 |
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