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Therapeutic Opportunities of Targeting Histone Deacetylase Isoforms to Eradicate Cancer Stem Cells

Cancer stem cells (CSCs), or tumor-initiating cells, are a small subset of cancer cells with the capacity for self-renewal and differentiation, which have been shown to drive tumor initiation, progression, and metastasis in many types of cancer. Moreover, therapeutic regimens, such as cisplatin and...

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Detalles Bibliográficos
Autores principales: Lin, Peng-Chan, Hsieh, Hao-Yu, Chu, Po-Chen, Chen, Ching S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073995/
https://www.ncbi.nlm.nih.gov/pubmed/30004423
http://dx.doi.org/10.3390/ijms19071939