Filamin C Truncation Mutations Are Associated With Arrhythmogenic Dilated Cardiomyopathy and Changes in the Cell–Cell Adhesion Structures

OBJECTIVES: The purpose of this study was to assess the phenotype of Filamin C (FLNC) truncating variants in dilated cardiomyopathy (DCM) and understand the mechanism leading to an arrhythmogenic phenotype. BACKGROUND: Mutations in FLNC are known to lead to skeletal myopathies, which may have an ass...

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Detalles Bibliográficos
Autores principales: Begay, Rene L., Graw, Sharon L., Sinagra, Gianfranco, Asimaki, Angeliki, Rowland, Teisha J., Slavov, Dobromir B., Gowan, Katherine, Jones, Kenneth L., Brun, Francesca, Merlo, Marco, Miani, Daniela, Sweet, Mary, Devaraj, Kalpana, Wartchow, Eric P., Gigli, Marta, Puggia, Ilaria, Salcedo, Ernesto E., Garrity, Deborah M., Ambardekar, Amrut V., Buttrick, Peter, Reece, T. Brett, Bristow, Michael R., Saffitz, Jeffrey E., Mestroni, Luisa, Taylor, Matthew R.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074050/
https://www.ncbi.nlm.nih.gov/pubmed/30067491
http://dx.doi.org/10.1016/j.jacep.2017.12.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074050/
https://www.ncbi.nlm.nih.gov/pubmed/30067491
http://dx.doi.org/10.1016/j.jacep.2017.12.003

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