Generation and Neuronal Differentiation of hiPSCs From Patients With Myotonic Dystrophy Type 2

Human induced pluripotent stem cells (hiPSCs)-patient specific are an innovative tool to reproduce a model of disease in vitro and summarize the pathological phenotype and the disease etiopathology. Myotonic dystrophy type 2 (DM2) is caused by an unstable (CCTG)n expansion in intron 1 of the CNBP ge...

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Detalles Bibliográficos
Autores principales: Spitalieri, Paola, Talarico, Rosa V., Murdocca, Michela, Fontana, Luana, Marcaurelio, Marzia, Campione, Elena, Massa, Roberto, Meola, Giovanni, Serafino, Annalucia, Novelli, Giuseppe, Sangiuolo, Federica, Botta, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074094/
https://www.ncbi.nlm.nih.gov/pubmed/30100878
http://dx.doi.org/10.3389/fphys.2018.00967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074094/
https://www.ncbi.nlm.nih.gov/pubmed/30100878
http://dx.doi.org/10.3389/fphys.2018.00967

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