Murine Retinal Citrullination Declines With Age and is Mainly Dependent on Peptidyl Arginine Deiminase 4 (PAD4)

PURPOSE: Citrullination is a post-translational modification (PTM) that serves many normal physiological functions. Studies have shown that this PTM—along with expression of the catalyzing enzymes, peptidyl arginine deiminases (PADs)—are increased in autoimmune and age-related pathologies. PAD2 reti...

Descripción completa

Detalles Bibliográficos
Autores principales: Hollingsworth, T. J., Radic, Marko Z., Beranova-Giorgianni, Sarka, Giorgianni, Francesco, Wang, Yanming, Iannaccone, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074612/
https://www.ncbi.nlm.nih.gov/pubmed/30073354
http://dx.doi.org/10.1167/iovs.18-24118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074612/
https://www.ncbi.nlm.nih.gov/pubmed/30073354
http://dx.doi.org/10.1167/iovs.18-24118

Ejemplares similares